Medicine is an ever．changing science．As new research and clinical experience broaden our knowledge， changes in treatment and drug therapy are required．The editors and the publisher of this work have checked with sources believed to be reliable in their efforts to provide information that iS complete and generally in ac。 cord with the standards accepted at the time of publication．However，in view of the possibility of human error or changes in medical sciences，neither the editors nor the publisher nor any other party who has been involved in the preparation or publication of this work warrants that the information contained herein IS in every respect accurate or complete，and they are not responsible for any errors or omissions or for the results obtained from use of such information．Readers are encouraged to confirm the information contained herein with other sources．For example and in particular，readers are advised to check the product lnformafion sheet included In the package of each drug they plan to administer tO be certain that the lnformation conmined in this book IS ac。 curate and that changes have not been made in the recommended dose or in the contraindications tor adrmms‘ tration．TlliS recommendation is of particular importance in connection wlth new or intrequently used drugs.