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Toll-Like Receptors in Inflammation 在线电子书 pdf 下载 txt下载 epub 下载 mobi 下载 2024

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O'Neill, Luke A. J. (EDT)/ Brint, Elizabeth (EDT) 作者

Springer Verlag

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出版日期

244 页数

$ 213.57 价格

HRD

丛书系列

9783764372859 图书编码

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发表于2024-11-27

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Toll-Like Receptors in Inflammation 在线电子书 epub 下载 mobi 下载 pdf 下载 txt 下载 2024

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A repertoire of 10 TLRs mediate the first response to all microbes that infect mammals. They are the long sought receptors for a wide range of microbial products. Notable examples include TLR4 which recognizes LPS from gram negative bacteria, TLR3 which recognizes viral double-stranded RNA and TLR9 which recognizes CpG DNA motifs, found commonly in both viruses and bacteria. TLRs are increasingly being implicated in both infectious and inflammatory diseases, notable examples being sepsis, inflammatory bowel disease, atherosclerosis and asthma. There is therefore great interest in targeting TLRs therapeutically since blocking TLRs will result in a decrease in the production of inflammatory mediators such as TNF. This volume covers our current understanding of TLRs, and their role in inflammation. Given the primacy of TLRs in the inflammatory process and their emerging role in inflammatory diseases the book is of great interest to researchers working in inflammation and immunology.

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