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Cancer Drug Resistance 在线电子书 pdf 下载 txt下载 epub 下载 mobi 下载 2024

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Teicher, Beverly A. 编作者

Humana Pr Inc

译者

2006-3 出版日期

640 页数

$ 292.67 价格

HRD

丛书系列

9781588295309 图书编码

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发表于2024-09-19

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Cancer Drug Resistance 在线电子书 epub 下载 mobi 下载 pdf 下载 txt 下载 2024

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Cancer Drug Resistance 在线电子书图书描述

Leading experts summarize and synthesize the latest discoveries concerning the changes that occur in tumor cells as they develop resistance to anticancer drugs, and suggest new approaches to preventing and overcoming it. The authors review physiological resistance based upon tumor architecture, cellular resistance based on drug transport, epigenetic changes that neutralize or bypass drug cytotoxicity, and genetic changes that alter drug target molecules by decreasing or eliminating drug binding and efficacy. The highlights include new insights into resistance to antiangiogenic therapies, oncogenes and tumor suppressor genes in therapeutic resistance, cancer stem cells, and the development of more effective therapies. There are also new findings on tumor immune escape mechanisms, gene amplification in drug resistance, the molecular determinants of multidrug resistance, and resistance to taxanes and Herceptin.

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