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Toxicokinetics and Risk Assessment 在线电子书 pdf 下载 txt下载 epub 下载 mobi 下载 2024

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Ohanian, Edward V. (EDT)/ Ohanian, Edward V. 作者

Taylor & Francis

译者

2006-10 出版日期

361 页数

$ 203.34 价格

HRD

丛书系列

9780849337222 图书编码

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Toxicokinetics and Risk Assessment 在线电子书 epub 下载 mobi 下载 pdf 下载 txt 下载 2024

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Toxicokinetics in Risk Assessment discusses the noncancer risk assessment process and its reliance on uncertainty factors in order to facilitate the continued study and refinement of the scientific basis for health risk assessment. This text clearly demonstrates the application of physiologically-based pharmacokinetic (PBPK) modeling in human health risk assessment, as well as methods for data generation, extrapolation, and inclusion of laboratory results for chemical metabolism and computer-based predictions of biochemical constants to address estimates of variability between experimental animals and humans. This guide also includes recent examples of the use of toxicokinetic information to successfully replace default values for uncertainty factors with data-derived factors in risk assessments developed by the US Environmental Protection Agency.

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