Myeloid Leukemia

Myeloid Leukemia pdf epub mobi txt 电子书 下载 2025

出版者:Humana Pr Inc
作者:Iland, Harry (EDT)/ Hertzberg, Mark (EDT)/ Marlton, Paula (EDT)
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页数:320
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出版时间:2005-11
价格:$ 224.87
装帧:HRD
isbn号码:9781588294852
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A panel of internationally recognized research scientists and clinical investigators brings together a diverse collection of readily reproducible methods for identifying and quantifying a large number of specific genetic abnormalities associated with the broad spectrum of myeloid malignancies. Highlights include techniques for the detection of BCR-ABL mutations and resistance to imatinib mesylate, detection of the FIP1L1-PDGFRA fusion in idiopathic hypereosinophilic syndrome and chronic eosinophilic leukemia, classification of AML by DNA-oligonucleotide microarrays, and detection of the V617F JAK2 mutation in myeloproliferative disorders. In addition to gene rearrangements, other prognostically relevant molecular lesions such as FLT3 mutations and WT-1 overexpression are covered.

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