Basic and Clinical Neurocardiology 在线电子书 pdf 下载 txt下载 epub 下载 mobi 下载 2025


Basic and Clinical Neurocardiology

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Armour, J. Andrew (EDT)/ Ardell, Jeffrey L. (EDT) 作者
Oxford Univ Pr
译者
2004-5 出版日期
478 页数
$ 101.70 价格
HRD
丛书系列
9780195141290 图书编码

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发表于2025-02-07


Basic and Clinical Neurocardiology 在线电子书 epub 下载 mobi 下载 pdf 下载 txt 下载 2025

Basic and Clinical Neurocardiology 在线电子书 epub 下载 mobi 下载 pdf 下载 txt 下载 2025

Basic and Clinical Neurocardiology 在线电子书 pdf 下载 txt下载 epub 下载 mobi 下载 2025



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The progression of heart disease is associated with changes in the neurohumoral mechanisms that control cardiac function. The degree to which this neurohumoral remodelling occurs, even before overt signs of cardiac disease become manifest, is important for prognosis. To determine why some patients experience sudden death while others sustain life in the presence of severely compromised cardiac function, the neuronal control of cardiac electrical and mechanical events must be considered. Starting at the level of individual neurons and building upwards, this book describes the synergistic interactions that occur among intrathoracic and CNS feedback loops to permit precise control of regional cardiac behaviour. On this basic science foundation, subsequent clinical chapters explore the remodelling that occurs in this system with ageing, with the evolution of specific cardiac pathologies, and with the psychological concomitants of heart disease. Most importantly, these chapters provide unique insights into how specific therapies like beta-andrenergic receptor blockade not only affect cardiomyocytes directly but also mitigate the adverse neurohumoral changes that accompany disease processes, such as heart failure and essential hypertension. The paradigm advanced in this volume is that heart disease is a multifaceted phenomenon involving the interplay of neurohumoral, cardiomyocyte and structural elements, each of which depends on the other. With our cumulative understanding of these interdependent processes, new avenues for time-appropriate, targeted methods of treating heart diseases can be developed.

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