Decoding the Genomic Control of Immune Reactions 在线电子书 pdf 下载 txt下载 epub 下载 mobi 下载 2024

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Novartis Foundation 作者

John Wiley & Sons Inc

译者

2007-5 出版日期

232 页数

132.00 元价格

HRD

丛书系列

9780470027554 图书编码

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发表于2024-11-10

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Decoding the Genomic Control of Immune Reactions 在线电子书 epub 下载 mobi 下载 pdf 下载 txt 下载 2024

Decoding the Genomic Control of Immune Reactions 在线电子书 pdf 下载 txt下载 epub 下载 mobi 下载 2024

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Decoding the Genomic Control of Immune Reactions 在线电子书图书描述

This book explores existing and potential strategies for using the genome sequences of human, mouse, other vertebrates and human pathogens to solve key problems in the treatment of immunological diseases and chronic infections. The assembled genome sequences now provide important opportunities for solving these problems, but a major bottleneck is the identification of key sequences and circuits controlling the relevant immune reactions.This will require innovative, interdisciplinary and collaborative strategies of a scale and complexity we are only now beginning to comprehend. Specific problems addressed include the following: What kinds of information are we lacking to understand how the genome sequence specifies the differentiation and response of immune system cells, and system behaviour such as immunological memory and tolerance? Which genome sequences and cellular circuits cause or prevent pathological immune responses to foreign pathogens, allergens or self-tissues? Which host and pathogen genome sequences and cellular circuits explain the failure of sterilizing immune responses to sophisticated human pathogens such as the agents of tuberculosis, malaria, metazoan parasites and chronic viruses? Containing contributions from a range of leading experts in the field, this book provides an important new perspective for clinical immunologists and basic researchers alike.

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