Genome Instability in Cancer Development 在线电子书 pdf 下载 txt下载 epub 下载 mobi 下载 2024

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Nigg, Erich A. 编作者

Springer Verlag

译者

2005-10 出版日期

528 页数

$ 213.57 价格

HRD

丛书系列

9781402037634 图书编码

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发表于2024-11-10

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Genome Instability in Cancer Development 在线电子书 epub 下载 mobi 下载 pdf 下载 txt 下载 2024

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Genome Instability in Cancer Development 在线电子书图书描述

This book reviews both genetic and biochemical data on the origin of genome instability and its impact on carcinogenesis. Reflecting recent discoveries and ongoing research, it discusses DNA repair mechanisms and hereditary cancer syndromes, as well as checkpoint mechanisms operating to safeguard chromosome integrity during cell cycle progression. Moreover, it summarises our current understanding of the various defects that may allow cancer cells to rapidly accumulate critical mutations and evolve, through processes reminiscent of Darwinian selection, an increasingly aggressive behaviour. Hopefully, this book will stimulate thought, discussion and experimentation, and serve as a rich source of information for a wide audience, including advanced students, researchers and clinical oncologists.

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