Pharmacophores and Pharmacophore Searches 在線電子書 pdf 下載 txt下載 epub 下載 mobi 下載 2024

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Hoffmann, Remy D. 編作者

Wiley-VCH

譯者

2006-10-30 出版日期

375 頁數

USD 225.00 價格

Hardcover

叢書系列

9783527312504 圖書編碼

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發表於2024-09-09

Pharmacophores and Pharmacophore Searches 在線電子書 epub 下載 mobi 下載 pdf 下載 txt 下載 2024

Pharmacophores and Pharmacophore Searches 在線電子書 epub 下載 pdf 下載 mobi 下載 txt 下載 2024

Pharmacophores and Pharmacophore Searches 在線電子書 pdf 下載 txt下載 epub 下載 mobi 下載 2024

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Pharmacophores and Pharmacophore Searches 在線電子書 pdf 下載 txt下載 epub 下載 mobi 在線電子書下載

Pharmacophores and Pharmacophore Searches 在線電子書圖書描述

This handbook is the first to address the practical aspects of this novel method. It provides a complete overview of the field and progresses from general considerations to real life scenarios in drug discovery research. Starting with an introductory historical overview, the authors move on to discuss ligand-based approaches, including 3D pharmacophores and 4D QSAR, as well as the concept and application of pseudoreceptors. The next section on structure-based approaches includes pharmcophores from ligand-protein complexes, FLIP and 3D protein-ligand binding interactions. The whole is rounded off with a complete section devoted to applications and examples, including modeling of ADME properties. With its critical evaluation of pharmacophore-based strategies, this book represents a valuable aid for project leaders and decision-makers in the pharmaceutical industry, as well as pharmacologists, and medicinal and chemists.

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