Are Older Adults Prescribed Too<br > Many Drugs?<br >There are 42.3 million older adults, that is, O 24% used a gastrointestinal drug (for<br >people 60 and over, living in the United ulcers, constipation, colitis, etc.).7<br >States.I In 1991, older Americans filled 650 An even larger proportion of older adults<br >million prescriptions for drugs at retail in nursing homes were being given drugs<br >drugstores, for an average of 15.4 prescrip- in each of these therapeutic categories,<br >tions per person.2 Thus, although people especially the mind-altering drugs which<br >60 and over make up just 16.7%, one-sixth, were used by 61% of 65 to 84-year-olds.<br >of the population, they use 38.5%, of the Although older adults do have more<br >prescription drugs3 at an annual cost of chronic diseases than those who are<br >well over $14.5 billion. All other Ameri- younger and therefore may need more<br >cans got an average of only 4.9 prescrip- drugs than younger people, there is mount-<br >tions per year, less than one-third as many ing evidence that many of our older citi-<br >as older adults.4 zens are getting prescription drugs which<br > Another way of looking at the problem of are entirely unnecessary (the wrong diag-<br >too many drugs for older adults is to ask how nosis has been made or nondrug therapy<br >many different drugs an average person takes would work), they are getting a more<br >in a year, since some of the 15.4 prescriptions dangerous drug when a much less danger-<br >per person are refills. A survey of older adults, ous one would work (a Worst Pill, instead<br >this time people 65 and over, found that 61% of a safer pill), or a lower dose of the same<br >of people 65-84 years old dwelling in the drug would give the same benefits with<br >community (not in nursing homes or the lower risks.<br >hospital) got three or more different pre- A very serious problem concerning the<br >scription drugs in a year, 37% got five or use of drugs by older adults is that many of<br >more, and 19% got seven or more different the "illnesses" for which they seek and are<br >drugs? (In nursing homes, an even larger, given drug treatment are problems which<br >proportion of people were given an extraordi- are, in fact, adverse drug reactions to drugs<br >nary number of drugs, with 34% of 65- to already being used which were not recog-<br >84-year-old residents getting seven or more nized by either patient or doctor as such.<br >different prescription drugs in a year.)6 In Chapter 2, Adverse Drug Reactions,<br > Yet another way of measuring the extent p. 9, we list common adverse drug reactions<br >of prescription drug use by older adults is which might be mistaken for diseases in<br >to find out what percentage are using older people. These "diseases," in this case<br >different categories of drugs. The same drug-induced, include memory loss, confu-<br >study mentioned above found that: sion, depression, parkinsonism, falls and<br >O 65% of people 65 to 84 (who were not in hip fractures, constipation, and urinary<br > nursing homes or hospitals) took a incontinence. We list, for each kind of<br > cardiovascular drug (for heart disease, adverse reaction, the drugs that have been<br > high blood pressure, or other heart/ shown to cause it.<br > blood vessel diseases) and 33% used a A recent review of 19 studies measuring<br > psychotropic drug (tranquilizer, sleeping the appropriateness of medication use on<br > pill, or antidepressant); the elderly -- looking at the prescribing<br >
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这本书简直是为我们这些步入高龄的人量身定做的!我一直觉得,随着年龄增长,身体机能下降,吃药这件事就成了一把双刃剑。一方面,很多慢性病确实需要药物来控制,不然生活质量会直线下降;另一方面,每次去药房拿药,看着那一大堆说明书,心里就犯嘀咕,生怕哪个不起眼的成分会和我正在服用的其他药产生冲突,或者干脆对我这把老骨头产生什么意想不到的副作用。这本书的出现,简直就像在迷雾中点亮了一盏明灯。它没有那种故作高深的医学术语,语言平实易懂,就像邻家经验丰富的老药剂师在跟你唠家常一样,把那些复杂的药物相互作用、潜在风险掰开揉碎了讲给你听。我特别欣赏作者那种直击核心的坦诚态度,他们毫不避讳地指出,有些我们习以为常的、甚至是医生开出的“常用药”,在特定情况下对老年人来说,简直就是“定时炸弹”。这种警示作用非常关键,它让我开始重新审视我那个塞得满满的药盒,不再盲目迷信“药到病除”的说法,而是学会了更谨慎地提问、更积极地与我的主治医生探讨替代方案。这本书不是要我们拒绝用药,而是教我们如何“聪明地用药”,如何最大程度地规避那些可能悄无声息毁掉健康的“最坏的药丸”。
评分拿到这本书的时候,我原本是抱着一种“看看老一套的健康建议”的心态的,毕竟市面上这类书籍太多了,内容往往大同小异,无非就是多运动、多吃蔬菜。然而,这本书的深度和广度完全超出了我的预期。它真正深入到了老年人特有的生理代谢特点这个核心问题。我们知道,随着年纪增长,肝脏和肾脏的功能都会自然衰退,这意味着药物在体内的代谢和排泄速度都会变慢,有效剂量和毒性剂量之间的“安全区间”变得极其狭窄。这本书没有停留在泛泛而谈的层面,而是针对性地列举了那些在老年群体中高发的不良反应,比如镇静剂导致的跌倒风险增加、某些降压药引发的体位性低血压,以及抗组胺药可能带来的认知障碍。更让我印象深刻的是,它不仅指出了问题,还提供了大量的“替代方案”或“注意事项”。比如,如果一定要用某种药物,那么起始剂量应该如何调整,或者在服用时需要监测哪些特定的指标。这种实用性,对于那些需要长期服药的患者来说,简直是无价之宝。它让我意识到,我的健康管理需要从“被动接受”转变为“主动参与”,而这本书就是我手中的“武器”。
评分我是一个非常注重生活质量的人,衰老是不可避免的,但我希望我的晚年是充实和清醒的,而不是被药物副作用折磨得神志不清或身体机能不断衰退。这本书正是致力于保护我们“高质量的老年生活”。它所强调的,不仅仅是“活得久”,更是“活得好”。作者在书中反复强调,许多被认为是“衰老正常现象”的症状,比如记忆力下降、嗜睡、平衡感变差,实际上很可能是药物不良反应的伪装。这种视角上的颠覆性,让我茅塞顿开。我立刻回想起过去几年里,因为吃了某种安眠药而导致的第二天整天昏昏沉沉的状态,原来那不是自然疲倦,而是药物的残留影响!这本书提供了一种全新的思维模式:在出现任何新的不适时,我们首先要做的不是增加新药,而是退回去检查我们正在服用的药物清单。它教会我们如何成为自己健康状况的“首席执行官”,通过审慎地管理自己的药物摄入,来最大限度地保持头脑的清晰和身体的活力,避免因为错误的用药策略而被药物“谋杀”或“拖垮”。
评分这本书的结构组织得非常清晰,这一点对于我们这些需要快速查找信息的人来说至关重要。它没有按照疾病分类来写,而是直接聚焦于“哪些药要警惕”,这才是最实用的。我喜欢它那种“对事不对人”的写作风格,它不是在指责医生开错药,而是指出在特定的药理背景下,某些药物组合或剂量需要高度警惕。每当提到一种“高风险药物”时,作者都会非常详尽地说明其作用机制、在老年人体内的代谢特点、可能导致的具体不良后果,以及更安全的替代选择。这种结构设计让我在查阅特定药物信息时,能够迅速定位到我需要知道的全部内容,省去了我大海捞针般的搜索过程。特别是对于那些患有多种慢性病、需要服用五种以上药物的“多重用药”的老年朋友来说,这本书提供的风险矩阵分析,简直就是一份救命指南。它帮助我们理清了错综复杂的用药网络,识别出那些潜伏在日常服药中的“定时引爆点”。
评分坦白说,我一开始对这种带有“警告”性质的书名有点抗拒,总觉得晦气,但读了几页之后,我就被作者那种强烈的责任感所打动了。这绝对不是一本为了哗众取宠而写出来的书,它背后一定付出了巨大的研究和梳理工作。书中的很多信息点,我之前在医院的宣传单上从未见过,或者一笔带过。例如,它详细分析了某些非处方药(OTC)的“隐形风险”,这些药我们可能觉得吃了没事,但实际上可能与我们正在服用的处方药产生了“协同毒性”。比如,常见的感冒药中的某些成分,对于心脏功能本就虚弱的老年人来说,可能就是压垮骆驼的最后一根稻草。作者用近乎批判性的眼光,重新审视了药物的“安全性评估”标准,强调了老年人临床试验数据缺乏的现实困境。这本书的价值在于,它替我们老年人发出了声音,要求医疗系统和制药行业对我们的特殊生理状态给予更多的关注和更精细化的指导。读完之后,我感觉自己不再是医疗流程中的一个被动接受者,而是一个有权知情并做出选择的“消费者”。
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