Drug Bioavailability 在线电子书 pdf 下载 txt下载 epub 下载 mobi 下载 2024

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Van De Waterbeemd, Han (EDT)/ Testa, Bernard (EDT) 作者

Wiley-VCH

译者

2008-11-24 出版日期

649 页数

USD 275.00 价格

Hardcover

丛书系列

9783527320516 图书编码

Drug Bioavailability 在线电子书图书标签: pharmaceutics

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Drug Bioavailability 在线电子书 epub 下载 mobi 下载 pdf 下载 txt 下载 2024

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Drug Bioavailability 在线电子书 pdf 下载 txt下载 epub 下载 mobi 在线电子书下载

Drug Bioavailability 在线电子书图书描述

The gold standard for industrial research now completely revised in line with current trends in the field, with all contributions extensively updated or rewritten.

In 21 chapters readers can benefit from the key working knowledge of today's leading pharmaceutical companies, including Pfizer, AstraZeneca, and Roche. Drug developers from industry and academia present all the factors governing drug bioavailability, complete with practical examples and real-life data.

Part I focuses on in vitro and in vivo measurements of physicochemical properties, such as membrane permeability and ionization. Part II discusses solubility and gastrointestinal absorption, while the third part is devoted to metabolism and excretory mechanisms. The much revised and expanded part IV surveys current in silico approaches to predict drug properties needed to estimate the bioavailability of any new drug candidate. The final part shows how poor bioavailability may be improved by various approaches during the development process.

No other publication offers the same level of treatment on this crucial topic in modern drug development.

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