The Somatotrophic Axis in Brain Function 在线电子书 pdf 下载 txt下载 epub 下载 mobi 下载 2024

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Nyberg, Fred 编作者

译者

2005-12 出版日期

384 页数

$ 259.90 价格

丛书系列

9780120884841 图书编码

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发表于2024-11-09

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The Somatotrophic Axis in Brain Function 在线电子书 epub 下载 mobi 下载 pdf 下载 txt 下载 2024

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The somatotropic axis is one of the major hormonal systems regulating postnatal growth in mammals. It interacts with the central nervous system on several levels. Growth hormone (GH) and insulin-like growth factor-I (IGF-I) receptors are expressed in many brain areas including the hippocampus, pituitary and hypothalamus. GH and IGF-I are important factors in the development and differentiation of the CNS and have protective properties in dementia, as well as in traumatic and ischaemic injury of the CNS. Also GH has an important impact on mood and well-being with GH secretory capacity being reduced in depression. This volume will include chapters on basic knowledge on GH/IGF-1, on localization of GH/IGF-1 and their receptors in the CNS, including blood brain barrier transport of both hormones, on actions of the two hormones on CNS function (basic science), on clinical aspects of GH/IGF-1 in relation to various CNS functions and disorders, and finally on some future perspectives in this area of science. The contents are well balanced and cover a variety of relevant topics from basic to clinical research. This book features an international selection of authors, with a good representation of the research on growth hormones. It is a timely publication which will be useful to scientists in both basic and clinical research.

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