EGFR Signaling Networks in Cancer Therapy 在线电子书 pdf 下载 txt下载 epub 下载 mobi 下载 2025

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Haley, John D. 编作者

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2008-10 出版日期

404 页数

$ 224.87 价格

丛书系列

9781588299482 图书编码

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发表于2025-06-04

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EGFR Signaling Networks in Cancer Therapy 在线电子书 epub 下载 mobi 下载 pdf 下载 txt 下载 2025

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The epidermal growth factor (EGF) receptor and its downstream signal transduction networks have been implicated in the ontology and maintenance of tumor tissues, which has motivated the discovery and development of molecularly targeted anti-EGFR therapies. Edited by John Haley and William J. Gullick, EGFR Signaling Networks in Cancer Therapy, is separated into two sections. The first of which probes the molecular pathways and the intersection of signaling networks which are frequently deregulated in human cancers, with a view to describing EGF receptor in a tumor tissue specific context. Meanwhile, the second section illustrates the many ways in which EGF receptor contribute to abnormal survival and migration signaling in cancer cells and to epithelial to mesenchymal transition and metastasis. The book also describes the mitogenic, survival, adhesive and migratory pathways within a framework of interacting subsystems that contribute to the activity and physiological regulation of the receptor in normal and neoplastic tissues. Even though there is still much to learn, this volume explores this fascinating system with compelling information.

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