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Zugel, Ulrich 编作者

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出版日期

185 页数

$ 101.64 价格

丛书系列

9783540735007 图书编码

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发表于2025-01-10

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Sparking Signals 在线电子书 epub 下载 mobi 下载 pdf 下载 txt 下载 2025

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Protein phosphorylation is an essential post-translational modification that modulates cella "cell communication. Substrate phosphorylation by protein kinases controls intracellular signal transduction pathways that mediate cell proliferation, migration, differentiation, and metabolism. The importance of the protein kinase family is underscored by numerous disease states that arise due to dysregulation of kinase activity. Recent progress in understanding the molecular regulation of kinases has led to the development of new therapeutics based on the inhibition of kinase activity. Inhibitors that target protein kinases have proven efficacious in clinical settings and their continued development is the current focus of many drug discovery groups.

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