SAS/Genetics is a collection of SAS procedures along with a SAS macro specifically designed for the statistical analysis of genetic marker data. This set of tools enables you to genetically dissect a complex disease or trait by analyzing marker data in a commonly collected form using the familiar SAS environment. This guide is intended to provide you with the statistical genetics background and the procedural syntax needed to use this software, as well as examples showing some common applications of the methods in these procedures. These methods include marker statistics such as measures of heterozygosity and allele and genotype frequencies, tests for disequilibrium both within and between markers, the analysis of marker-trait relationships in case-control or pedigree data, and algorithms for estimating haplotype frequencies from genotype data. This guide also demonstrates how to obtain a graphical representation of the procedures' results using a new SAS macro. This title is also available online. This guide is intended for those with at least a basic understanding of statistical and genetic concepts who are interested in analyzing genetic marker data either from a population genetics or a genetic epidemiology perspective. Supports releases 9.1 and higher of SAS software.
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