Medicine is all ever-changing scienee．As new research and clinical experience broaden our knowledge， changes in treatment and drug therapy are required．The authors and the publisher of this work have checked with sources believed to be reliable in their efforts to provide information that is complete and generally in accord with the standards accepted at the time of publlcafion．However，in view of the possi- bility of human error or changes in medical sciences．neither the authors nor the publisher nor any other party who has been involved in the preparation or publication of this work warrants that the information contained herein is in every respect accurate or complete．and they disclaim all responsibility for any errors or omissions or for the results obtalned from use of the information contained in this work． Readers are encouraged to confirm the information contained herein with other sources．For example and in particular．readers ale advised to check the product information sheet included in the package of each drug thev plan to administer to be certain that the information contained in this work is accurate and that changes have not been made in the recommended dose or in the contraindications for administration． ThiS recommendation is of particular importance in connection with new or infrequently used drugs． This bookwas setinTimesRomanbyPineTreeComposition．