Selective Estrogen Receptor Modulators 在线电子书 pdf 下载 txt下载 epub 下载 mobi 下载 2024

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Calaf I. Alsina, Joacquim 编作者

Springer

译者

2006-07-26 出版日期

357 页数

USD 169.00 价格

Hardcover

丛书系列

9783540242277 图书编码

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The experience gained with tamoxifen has been the basis for the new concept of selective estrogen receptor modulators (SERMs). The action of these substances has been investigated in both basic and clinical studies, but there is not an integrated view of all the facets of this recent area in modern medicine. This book offers an up-to-date compilation of the most relevant information on the topic carried out by experienced basic and clinical investigators. The first section revises the basic determinants required to understand the functional versatility of SERMs. This part includes chapters that review the main SERM families and their principal components, the mechanisms of action of steroid hormones, SERMs and pure antiestrogens, or and the action of SERMs on the hypothalamic-pituitary unit. The second part focuses on the clinical areas where SERMs have demonstrated efficacy, such as osteoporosis, breast cancer, cardiovascular disease, and benign gynecological pathology, including actions on the endometrium, etc. There is a final chapter offering a thoughtful reflection on the role that SERMs may have in clinical practice.

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