The Drug Hunters pdf epub mobi txt 电子书 下载 2025
Dr. Donald R. Kirsch has been a drug hunter for thirty five years, holds twenty-four drug-related patents, has written more than fifty papers, has been a reviewer for prestigious journals, a director, research group leader, and chief science officer at Wyeth, Cyanamid, Squibb, and Cambria Pharmaceuticals, and currently teaches drug discovery at Harvard Extension School. He lives in Bedford, MA.
Ogi Ogas, PhD, is a professional science writer. He is the coauthor of A Billion Wicked Thoughts and Shrinks and has published articles in the Wall Street Journal, Boston Globe, Wired, Glamour, Seed, and Psychology Today. He lives in Boston, MA.
- 药物
- 经济,政治和历史
- 科普
- 科学和心理学
- 制药
- Medical
The surprising, behind-the-scenes story of how our medicines are discovered, told by a veteran drug hunter.
The search to find medicines is as old as disease, which is to say as old as the human race. Through serendipity— by chewing, brewing, and snorting—some Neolithic souls discovered opium, alcohol, snakeroot, juniper, frankincense, and other helpful substances. Ötzi the Iceman, the five-thousand-year-old hunter frozen in the Italian Alps, was found to have whipworms in his intestines and Bronze-age medicine, a worm-killing birch fungus, knotted to his leggings. Nowadays, Big Pharma conglomerates spend billions of dollars on state-of the art laboratories staffed by PhDs to discover blockbuster drugs. Yet, despite our best efforts to engineer cures, luck, trial-and-error, risk, and ingenuity are still fundamental to medical discovery.
The Drug Hunters is a colorful, fact-filled narrative history of the search for new medicines from our Neolithic forebears to the professionals of today, and from quinine and aspirin to Viagra, Prozac, and Lipitor. The chapters offer a lively tour of how new drugs are actually found, the discovery strategies, the mistakes, and the rare successes. Dr. Donald R. Kirsch infuses the book with his own expertise and experiences from thirty-five years of drug hunting, whether searching for life-saving molecules in mudflats by Chesapeake Bay or as a chief science officer and research group leader at major pharmaceutical companies.
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读后感
“每种获得美国食品药品监督管理局认可的药物平均要花费15亿美元和14年时间,大型制药公司越来越不愿意花费巨额研发费用,因为大部分砸进去的钱最终都打了水漂。最近辉瑞的高管告诉我,他们正在考虑是否彻底退出医药研发领域,只买别人研发出来的现成药。” 01 — 简明扼要回顾人类...
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很有意思的书，非常浅显好读。作为前化工工程师，能深刻体会drug hunter们的艰辛，而成药上市的难度对比化工品的研发又是云泥之别了。运气确实比智慧更重要。
评分很有意思的书，非常浅显好读。作为前化工工程师，能深刻体会drug hunter们的艰辛，而成药上市的难度对比化工品的研发又是云泥之别了。运气确实比智慧更重要。
评分很有意思的书，非常浅显好读。作为前化工工程师，能深刻体会drug hunter们的艰辛，而成药上市的难度对比化工品的研发又是云泥之别了。运气确实比智慧更重要。
评分很有意思的书，非常浅显好读。作为前化工工程师，能深刻体会drug hunter们的艰辛，而成药上市的难度对比化工品的研发又是云泥之别了。运气确实比智慧更重要。
评分很有意思的书，非常浅显好读。作为前化工工程师，能深刻体会drug hunter们的艰辛，而成药上市的难度对比化工品的研发又是云泥之别了。运气确实比智慧更重要。
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