GTPases Regulating Membrane Targeting and Fusion 在線電子書 pdf 下載 txt下載 epub 下載 mobi 下載 2024

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Balch, W. E. (EDT)/ Der, Channing J. (EDT)/ Hall, Alan (EDT) 作者

Academic Pr

譯者

2005-12 出版日期

912 頁數

$ 224.87 價格

HRD

叢書系列

9780121828080 圖書編碼

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發表於2024-11-24

GTPases Regulating Membrane Targeting and Fusion 在線電子書 epub 下載 mobi 下載 pdf 下載 txt 下載 2024

GTPases Regulating Membrane Targeting and Fusion 在線電子書 epub 下載 pdf 下載 mobi 下載 txt 下載 2024

GTPases Regulating Membrane Targeting and Fusion 在線電子書 pdf 下載 txt下載 epub 下載 mobi 下載 2024

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GTPases Regulating Membrane Targeting and Fusion 在線電子書 pdf 下載 txt下載 epub 下載 mobi 在線電子書下載

GTPases Regulating Membrane Targeting and Fusion 在線電子書圖書描述

Rab GTPases now comprise a family of >63 members. They are emerging as the key hub element controlling the membrane architecture of eukaryotic cells. They are intimately involved in vesicle targeting and fusion in both the endocytic and exocytic pathways and direct the assembly and disassembly of protein complexes that include regulators (GEFs and GAPs), effectors (tethers/motors) and fusion components (SNAREs) that control membrane targeting and fusion. During the last 3 years the field has virtually exploded with the identification and characterization of many new Rab proteins and their effectors. Our understanding of how Rab GTPases control membrane function remains at its infancy. This volume of MIE provides a wealth of new concepts, approaches and tools to study Rab proteins in the test tube and in living cells that will be of strong benefit to both established laboratories and new investigators in the field to elucidate Rab GTPase function in cellular development, differentiation and proliferation. It provides a comprehensive overview of Rab GTPase phylogeny and systems biology. It covers identification and characterization of Rab GEFs, GAPs and effectors. It offers general methodologies to study Rab GTPase function in vitro and in vivo using biochemical, molecular and microscopy approaches.

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