Hill is the author of ten books of fiction and non-fiction. In 2005, he won his first literary honour: a National Magazine Award for the article “Is Africa’s Pain Black America’s Burden?” published in The Walrus. His first two novels were Some Great Thing and Any Known Blood, and his first non-fiction work to attract national attention was the memoir Black Berry, Sweet Juice: On Being Black and White in Canada. But it was his third novel, The Book of Negroes (HarperCollins Canada, 2007) — published in some countries as Someone Knows My Name and in French as Aminata — that attracted widespread attention in Canada and other countries.

Lawrence Hill’s non-fiction book, Blood: The Stuff of Life was published in September 2013 by House of Anansi Press. Blood is a personal consideration of the physical, social, cultural and psychological aspects of blood, and how it defines, unites and divides us. Hill drew from the book to deliver the 2013 Massey Lectures across Canada.

In 2013, Hill published the essay Dear Sir, I Intend to Burn Your Book: An Anatomy of a Book Burning (University of Alberta Press).

His fourth novel, The Illegal, was published by HarperCollins Canada in 2015 and by WW Norton in the USA in 2016.

Hill is currently writing a new novel and a children’s book, and co-writing a television miniseries adaptation of The Illegal for Conquering Lion Pictures. Hill is a professor of creative writing at the University of Guelph, in Ontario.

Based on a true story, "The Book of Negroes" tells the story of Aminata, a young girl abducted from her village in Mali aged 11 in 1755, and who, after a deathly journey on a slave ship where she witnesses the brutal repression of a slave revolt, is sold to a plantation owner in South Carolina, who rapes her. She is brought to New York, where she escapes her owner, and finds herself helping the British by recording all the freed slaves on the British side in the Revolutionary War in The Book of Negroes (a real historical document that can be found today at the National Archives at Kew).Aminata is sent to Nova Scotia to start a new life, but finds more hostility, oppression and tragedy. Separated from her one true love, and suffering the unimaginable loss of both her children who are taken away from her, she eventually joins a group of freed slaves on a harrowing odyssey back to Africa, and ends up in London as a living icon for Wilberforce and the other Abolitionists. "The Book of Negroes" is a pageturning narrative that manages to use Aminata's heart-rending personal story to bring to life a harrowing chapter in our history.