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Molecular Basis of Pulmonary Disease 在线电子书 pdf 下载 txt下载 epub 下载 mobi 下载 2024

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McCormack, Frank (EDT) 作者

译者

2010-4 出版日期

444 页数

$ 292.67 价格

丛书系列

9781588299635 图书编码

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发表于2024-11-10

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Molecular Basis of Pulmonary Disease 在线电子书 epub 下载 mobi 下载 pdf 下载 txt 下载 2024

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One premise of this book is that the study of rare lung disorders enhances our understanding of common pulmonary diseases and disease mechanisms such as fibrosis and emphysema. For example, the finding that the mutations in the alveolar type II cell specific protein, SP-C, can lead to pulmonary fibrosis is prima facie evidence that the alveolar epithelium plays a critical role in fibrogenesis. Similiarly, development of premature emphysema in patients with alpha one antitrypsin deficiency provides strong support for the theory of protease/protease inhibitior balance in the pathogenesis of alveolar destruction. A second equally important premise is that the science in rare lung disease is inherently interesting and can often change with surprising speed. This is partly related to the fact that the genetic basis of many rare lung diseases is now available, providing a unique vantage point for framing research questions.

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