Progress in Medicinal Chemistry 在线电子书 pdf 下载 txt下载 epub 下载 mobi 下载 2024

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Lawton, G. (EDT)/ Witty, D. R. (EDT) 作者

Elsevier Science Ltd

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2008-5 出版日期

420 页数

$ 211.31 价格

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9780444530189 图书编码

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Progress in Medicinal Chemistry 在线电子书 epub 下载 mobi 下载 pdf 下载 txt 下载 2024

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Appropriate selection of biochemical targets is one of the most important drivers of cost effectiveness in the discovery of new medicines. Despite the many advances in genetics, genomics and systems biology, validation of a target is not achieved until therapeutic efficacy is demonstrated by a drug candidate.Volume 46 of this series reviews the medicinal chemistry aimed at six diverse targets from which important new medicines are emerging: HIV integrase (discovery of the first-in-class inhibitor drug raltegravir), 11-beta-Hydroxysteroid dehydrogenase (new approach to glucocorticoid regulation), nicotinic a7 choline receptor (agonists and positive allosteric modulators), bradykinin receptor (new approach to pain therapy); histone deacetylase (new drugs for cancer), and 5-HT2c receptor modulators (various CNS indications). This book presents the latest research in the field of drug discovery. It publishes on an annual basis to bring you the most innovative updates in medicinal chemistry. It is available as an online resource via ScienceDirect.

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