How are sights, sounds and smells converted into electrical signals in a form that can be interpreted by the nervous system? This process called sensory transduction began to be understood only recently as a result of the development of the techniques of patch clamp recording and gene cloning. Beginning with fundamental properties of ion channels and G protein coupled signal cascades, this text provides a comprehensive survey of this knowledge that, taken as a whole, represents one of the greatest achievements of modern biology and neuroscience: the unravelling of the mechanism of sensation.
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