Thrombotic and thromboembolic disorders are now more than ever the leading causes of morbidity and mortality, having become common medico-social problems with economic consequences in industrialized and developing countries alike. Particularly acute is thrombosis complicating lifestyle-related diseases such as malignancies and arteriosclerosis resulting from diabetes mellitus, hypertension, obesity, and related conditions. Expanding knowledge of molecular biology and genetics, however, is providing new possibilities in the regeneration and development of tissues, organs, and embryos. As well, bio-regulatory mechanisms in viable tissues are being developed to counter intrinsic and extrinsic stimuli in addition to cardiovascular diseases. This important book covers not only updated molecular biology and genetics but also the clinical implications of a better understanding of pathophysiology and the novel exploitation of diagnostic methodologies, with therapeutic applications. Also included are methods for prevention in thrombosis?hemostasis and atherosclerosis.
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