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Progress in Medicinal Chemistry 在线电子书 pdf 下载 txt下载 epub 下载 mobi 下载 2024

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King, F. D. (EDT)/ Lawton, G. (EDT)/ Oxford, A. W. (EDT) 作者

Elsevier Science Ltd

译者

2004-12 出版日期

450 页数

$ 205.66 价格

HRD

丛书系列

9780444511430 图书编码

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Progress in Medicinal Chemistry 在线电子书 epub 下载 mobi 下载 pdf 下载 txt 下载 2024

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This volume includes information on recent advances in five important areas: an account of inhibitors of the caspase family of proteolytic enzymes that represent a new class of anti-inflammatory and antiapoptotic agents of potential value in rheumatoid arthritis; and a survey of semi-synthetic and totally synthetic antibiotics and anti-HIV agents and their sites of interaction; the development of inhibitors of the intracellular enzyme acyl-CoA: cholesterol O-acyltransferase (ACAT) for the treatment of hypercholesterolemia; a description of recent progress in growth hormone secretagogues, with the focus on strategies to improve oral bioavailability and duration of action; and information on inhibition of the proteolytic enzyme, hepatitis C protease N-3(NS3), (required for vital replication) as one of the most attractive targets for HCV infections.

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