Brain Development 在线电子书 pdf 下载 txt下载 epub 下载 mobi 下载 2024


Brain Development

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Miller, Michael W. 编 作者
Oxford University Press
译者
2006-4-6 出版日期
424 页数
USD 130.00 价格
Hardcover
丛书系列
9780195183139 图书编码

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发表于2024-11-13


Brain Development 在线电子书 epub 下载 mobi 下载 pdf 下载 txt 下载 2024

Brain Development 在线电子书 epub 下载 mobi 下载 pdf 下载 txt 下载 2024

Brain Development 在线电子书 pdf 下载 txt下载 epub 下载 mobi 下载 2024



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This is the first book about both normal development of the nervous system and how early exposure to alcohol and nicotine interferes with this development. The developing nervous system is highly dynamic and vulnerable to genetic and epigenetic factors that can be additive or synergistic. Disruption of normal brain development leads to an array of developmental disorders. One of the most common of these is mental retardation, the prime cause of which is prenatal exposure to alcohol. As chapters in this book show, alcohol has direct effects on the developing neural system and it affects genetic regulation. Another common neurotoxin is nicotine, and it is discussed in this book for three reasons: (1) the number of adolescents who smoke cigarettes is rising in some populations; (2) prenatal exposure to nicotine affects neurotransmitter systems that are critical for normal brain development and cognition; and (3) prenatal exposure to nicotine is often accompanied by prenatal exposure to alcohol. The mature brain is the culmination of an orderly sequence of basic ontogenetic processes - cell proliferation, migration, differentiation, and death.Neural stem cells and progenitors proliferate in discreet sites; then, young neurons migrate long distances to their residences where they form neural networks. During this sequence many immature cells die, presumably eliminating unsuitable or non-competitive cells. Each process is regulated by genetic and environmental factors. When this regulation goes awry, a dysmorphic and dysfunctinoal brain results. Though this can be tragic in clinical settings, in experimental contexts it provides keen insight into normal brain development.

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