Junk DNA 在线电子书 图书标签: 科普 生物学 生物 表观遗传学 英文原版 科学和心理学 Non-Fiction JunkDNA
发表于2024-11-28
Junk DNA 在线电子书 pdf 下载 txt下载 epub 下载 mobi 下载 2024
很具有科普性质的一本书,Nesaa Carey用了很多简单易懂的例子来阐述,即便不是生物专业的人也能读懂。
评分类比用得太多,多数都很好,部分没必要,读着读着都快成我的pet peeve了。这里的Junk是指所有不合成蛋白质的DNA,这个定义远比我之前想的宽泛,也使得这本书内容非常繁杂,诸多归类和举例,以及各种疾病,但总结和升华性的文字不多;有些内容讲得较深,另一些却非常简化,这可能也跟目前相关认识有限有关,而本书介绍的多是被实证的东西,较少猜想。基于第一本书出版后读者的反馈,这次将许多基因的名字放脚注了,我觉得像第一本书那样更好。
评分很具有科普性质的一本书,Nesaa Carey用了很多简单易懂的例子来阐述,即便不是生物专业的人也能读懂。
评分很具有科普性质的一本书,Nesaa Carey用了很多简单易懂的例子来阐述,即便不是生物专业的人也能读懂。
评分对于人类还是不完全清楚的领域,这种科普书籍的确难写。专业的读者读觉得太浅显,非专业的读者又有可能完全看不懂。我的感受是,“存在即合理”,我们现有的科学探索能力把non-codingDNA为Junk,但是所有事物不都是:风光的(显著表达)就那么1-2%,其他的都是作为系统,提供平台滋养“精英”的吗?
Nessa Carey is a visiting professor at Imperial College, London, and earned her Ph.D. in virology from the University of Edinburgh. Having worked in the biotech and pharma industries for more than a decade, she maintains strong relationships with leading researchers in Europe and across the United States, at such institutions as the Harvard Medical School, the University of Pennsylvania, the Wistar Institute, MD Anderson Cancer Center, and the University of Southern California. Carey is also the author of The Epigenetics Revolution: How Modern Biology Is Rewriting Our Understanding of Genetics, Disease, and Inheritance.
For decades after identifying the structure of DNA, scientists focused only on genes, the regions of the genome that contain codes for the production of proteins. Other regions that make up 98% of the human genome were dismissed as "junk," sequences that serve no purpose. Yet recently researchers have discovered variations and modulations in this junk DNA that underwrite a number of intractable diseases. This knowledge has led to innovative research and treatment approaches that may finally control these conditions.
Junk DNA can play vital and unanticipated roles in the control of gene expression, from fine-tuning individual genes to switching off entire chromosomes. Its function has forced scientists to revisit the very meaning of the word "gene" and has engendered a bitter battle over whether or not this genomic "nonsense" is the source of human biological complexity. Drawing on her experience with leading investigators in Europe and North America, Nessa Carey provides a clear and compelling introduction to junk DNA and its critical involvement in phenomena as diverse as genetic diseases, viral infections, sex determination in mammals, disease treatments, and evolution. We are only now unlocking the secrets of junk DNA, and Carey's book is an indispensable resource for navigating the codes and controversies of this fast-growing and hotly disputed field.
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Junk DNA 在线电子书 pdf 下载 txt下载 epub 下载 mobi 下载 2024