Multiple Testing Procedures with Applications to Genomics pdf epub mobi txt 電子書下載2025

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出版者:Springer Verlag

作者:Dudoit, Sandrine/ Van Der Laan, Mark J.

出品人:

頁數:623

译者:

出版時間:2007-10

價格:$ 134.47

裝幀:HRD

isbn號碼:9780387493169

叢書系列:

圖書標籤:

美國
統計
科技
數學
教材
statistics
gene
R

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This book establishes the theoretical foundations of a general methodology for multiple hypothesis testing and discusses its software implementation in R and SAS. These are applied to a range of problems in biomedical and genomic research, including identification of differentially expressed and co-expressed genes in high-throughput gene expression experiments; tests of association between gene expression measures and biological annotation metadata; sequence analysis; and genetic mapping of complex traits using single nucleotide polymorphisms. The procedures are based on a test statistics joint null distribution and provide Type I error control in testing problems involving general data generating distributions, null hypotheses, and test statistics.