具体描述
Starred Review. Mukherjee's debut book is a sweeping epic of obsession, brilliant researchers, dramatic new treatments, euphoric success and tragic failure, and the relentless battle by scientists and patients alike against an equally relentless, wily, and elusive enemy. From the first chemotherapy developed from textile dyes to the possibilities emerging from our understanding of cancer cells, Mukherjee shapes a massive amount of history into a coherent story with a roller-coaster trajectory: the discovery of a new treatment--surgery, radiation, chemotherapy--followed by the notion that if a little is good, more must be better, ending in disfiguring radical mastectomy and multidrug chemo so toxic the treatment ended up being almost worse than the disease. The first part of the book is driven by the obsession of Sidney Farber and philanthropist Mary Lasker to find a unitary cure for all cancers. (Farber developed the first successful chemotherapy for childhood leukemia.) The last and most exciting part is driven by the race of brilliant, maverick scientists to understand how cells become cancerous. Each new discovery was small, but as Mukherjee, a Columbia professor of medicine, writes, "Incremental advances can add up to transformative changes." Mukherjee's formidable intelligence and compassion produce a stunning account of the effort to disrobe the "emperor of maladies." (Nov.) (c)
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作者简介
Siddhartha Mukherjee is a cancer physician and researcher. He is an assistant professor of medicine at Columbia University and a staff cancer physician at the CU/NYU Presbytarian Hospital. A former Rhodes scholar, he graduated from Stanford University, University of Oxford (where he received a PhD studying cancer-causing viruses) and from Harvard Medical School. His laboratory focuses on discovering new cancer drugs using innovative biological methods. Mukherjee trained in cancer medicine at the Dana Farber Cancer Institute of Harvard Medical School and was on the staff at the Massachusetts General Hospital. He has published articles and commentary in such journals as Nature, New England Journal of Medicine, Neuron and the Journal of Clinical Investigation and in publications such as the New York Times and the New Republic. His work was nominated for Best American Science Writing, 2000 (edited by James Gleick). He lives in Boston and New York with his wife, Sarah Sze, an artist, and with his daughter, Leela.
目录信息
Prologue 1
Part 1 "Of blacke cholor, without boyling" 9
Part 2 An Impatient War 105
Part 3 "Will you turn me out if I can't get better?" 191
Part 4 Prevention is the Cure 235
Part 5 "A Distorted Version of Our Normal Selves" 335
Part 6 The Fruits of Long Endeavors 393
Atossa's War 461
Acknowledgments 471
Notes 473
Glossary 533
Selected Bibliography 537
Photograph Credits 543
Index 545
· · · · · · (收起)
读后感
推荐《众病之王----癌症传》，大牛的科普读物。非常严谨，句子也好读，不晦涩。功课做得真足，年份什么的都好清楚。写作线索也非常明析。太喜欢看这种书了。作者是印裔米国人，把米国所有的牛叉学院都上了个遍。这书写了六年。超值。能把人类病史写得好的，还头一回看到。
评分本书的题记上说，美国1/3的女性和1/2的男性会得癌症。这样算来，一对夫妻终生不得癌症的概率仅为1/3，如再考虑双方的父母，一个人在一生中都不接触癌症患者的概率不会超过1/27。中国的数据和美国或有差异，但癌症早已是仅次于心脑血管病的国人第二大死因。考虑到癌症患者的痛苦...
评分1、“我们相信上帝，但其他人必须用数据说话。。”ipad版p250 2、叶酸抗结剂治疗白血病的故事。。 3、p253，医生目的不是挽救特定人，而是挽救所有人的生命。 4、苏珊桑塔格，疾病的隐喻 5、p263，狮子，狗，人类是仅知的会发生前列腺癌的动物。p265，化学阉割。 6、p285，再次...
评分很早就看完了，一直想要找个时间写这本书的书评，由于准备考研一直就把这个给拖后了。或许很多细节记得不是那么清楚了，我只想写写我看这本书的整个过程。 爸是在今年3月份查出癌症的，之前一直医生误以为是由于肾结石引起的左肾肿大变形，直到最后把左肾切除后做了活检才发现...
用户评价
这是一本癌症的传记，这个困扰了人类几千年的疾病。作者是个医生，专业知识扎实，文字又好，功课也做得足。虽然书并不短，但是用四百多页深入浅出的把癌症几千年的历史和近来几百年地医治和研究历讲的生动有力也不是易事。
评分伴随着我渡过了纽约律所实习时的地铁时光，有时晚上加班困极了，读着读着就睡着，醒来发现坐过了站，而夜太深local的列车又停运了，只得穿过许多街区走过哥大校园回到出租屋。现在都不知道，让我沮丧的，是关于癌症的论调，还是工作。想起曾经读到过的，别急着觉得自己一无所有，你还可以有病呢。
评分推荐购买。知识量很大，有机会再度一遍。
评分都说文学就是人学，读完此书意识到医学也是人学。Mukherjee似乎特别擅长抓住科学研究发展与时代背景之间的关系，而刻画一个个人物时又入骨般有力。读到War on Cancer折射出的坚定的信念与空虚的狂热，读到禁烟运动与烟草公司斡旋的艰难曲折，读到在理解癌症的基因基础之路上的抽丝剥茧，总忍不住眼红鼻酸。然而同样让我印象深刻的是书中一个个的人，从Larger than life的化疗之父Farber到无数被癌症改变了人生的病人。疾病可以成为隐喻，正是在于疾病作为一个独特的透镜反射出的人性。
评分Worth reading a second time
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