List of Contributors ix
Preface Gary Marcus and Jeremy Freeman xi
MAPPING THE BRAIN
Building Atlases of the Brain 3
Mike Hawrylycz with Chinh Dang, Christof Koch, and Hongkui Zeng
Whole Brain Neuroimaging and Virtual Reality 17
Misha B. Ahrens
Project MindScope 25
Christof Koch with Clay Reid, Hongkui Zeng, Stefan Mihalas, Mike Hawrylycz, John Philips, Chinh Dang, and Allan Jones
The Connectome as a DNA Sequencing Problem 40
Anthony Zador
Rosetta Brain 50
George Church with Adam Marblestone and Reza Kalhor
COMPUTATION
Understanding the Cortex through Grid Cells 67
May-Britt Moser and Edvard I. Moser
Recording from Many Neurons Simultaneously: From Measurement to Meaning 78
Krishna V. Shenoy
Network Neuroscience 90
Olaf Sporns
Large-Scale Neuroscience: From Analytics to Insight 100
Jeremy Freeman
SIMULATING THE BRAIN
Whole Brain Simulation 111
Sean Hill
Building a Behaving Brain 125
Chris Eliasmith
LANGUAGE
The Neurobiology of Language 139
David Poeppel
Translating the Genome in Human Neuroscience 149
Simon E. Fisher
Color plates follow p. 160
SKEPTICS
Consciousness, Big Science, and Conceptual Clarity 161
Ned Block
From Circuits to Behavior: A Bridge Too Far? 177
Matteo Carandini
Lessons from Evolution 186
Leah Krubitzer
Lessons from the Genome 194
Arthur Caplan with Nathan Kunzler
The Computational Brain 205
Gary Marcus
IMPLICATIONS
Neurotechnology 219
John Donoghue
The Miswired Brain, Genes, and Mental Illness 234
Kevin J. Mitchell
Neural Dust: An Untethered Approach to Chronic Brain-Machine Interfaces 243
Michel M. Maharbiz with Dongjin Seo, Jose M. Carmena, Jan M. Rabaey, and Elad Alon
AFTERWORD
Neuroscience in 2064: A Look at the Last Century 255
Christof Koch and Gary Marcus
Glossary 271
Index 275
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