"Bones and Cartilage" provides the most in-depth review ever assembled on the topic. It examines the function, development and evolution of bone and cartilage as tissues, organs and skeletal systems. It describes how bone and cartilage is developed in embryos and are maintained in adults, how bone reappears when we break a leg, or even regenerates when a newt grows a new limb, or a lizard a tail. This book also looks at the molecules and cells that make bones and cartilages and how they differ in various parts of the body and across species. It answers such questions as 'Is bone always bone?' 'Do bones that develop indirectly by replacing other tissues, such as marrow, tendons or ligaments, differ from one another?' 'Is fish bone the same as human bone?' 'Can sharks even make bone?' and many more. This book provides complete coverage of every aspect of bone and cartilage. It is full of interesting and unusual facts. This is the only book available that integrates development and evolution of the skeleton. It treats all levels from molecular to clinical, embryos to evolution. It is written in a lively, accessible style. It is extensively illustrated and referenced. It integrates analysis of differentiation, growth and patterning. It covers all the vertebrates as well as invertebrate cartilages. It identifies the stem cells in embryos and adults that can make skeletal tissues.
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