The Code Breaker 在線電子書 圖書標籤:
發表於2024-11-04
The Code Breaker 在線電子書 pdf 下載 txt下載 epub 下載 mobi 下載 2024
讀瞭Emmanuelle Charpentier, Feng Zhang, &He jiankui, CRISPR, Gene editing historic records部分,作者寫到science內容一筆帶過,想瞭解詳細內容自己去看文獻,曆史的部分講述得比較精彩,不搞學術的人讀瞭能看到研究進步發展時間綫上科學傢們的主導、參與、被遺忘、被放棄及存活的真實展現,good read
評分感覺看瞭一部宮鬥劇?
評分roadtrip上聽完瞭有聲書 比預計的更有意思更drama crispr齣來的時候 很多報道podcast采訪 biotech/genes也hype很久瞭 但都知道瞭些皮毛 這本書聽完纔覺得真的懂瞭些 science確實是很competitive的field 特彆是這些lab類的 發文章cycle還算快 就真的是分秒必爭 同事之間的閤作和競爭關係微妙 好奇如果有本從boston角度來講(vs. Berkeley)會是怎麼個態度 Isaacson很是細節之王 多少年前的事情 估計當事人都記不清楚瞭 他能寫細緻至極 feminism貫穿瞭整本書 最後幾章講gene editing moral的有點散
評分科普的部分已經在其它書裏見過瞭,傳記的部分又不是很有意思。
評分這本書的寫法太悶瞭,吸引人的反而是那些爭議角色,比如口無遮攔的沃森,或者死捧弟子的Eric Lander,其他角色都立不起來。好在crispr周圍的抓馬就算遇到這種筆觸也絲毫沒有減少八點檔特質。倫理部分非常淺,有大段絲毫沒有建設性的“上帝”“自然”討論,這都什麼年代瞭。在我看來社交網絡還邪惡得要死呢,但人傢已經在這裏瞭,好好拆分和針對性解決吧。有朝一日我一定能等來有個性有文筆還不談上帝的生物學傢重寫這段往事的
Walter Isaacson, a professor of history at Tulane, has been CEO of the Aspen Institute, chair of CNN, and editor of Time. He is the author of Leonardo da Vinci; The Innovators; Steve Jobs; Einstein: His Life and Universe; Benjamin Franklin: An American Life; and Kissinger: A Biography, and the coauthor of The Wise Men: Six Friends and the World They Made. Visit him at Isaacson.Tulane.edu.
The bestselling author of Leonardo da Vinci and Steve Jobs returns with a gripping account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies.
When Jennifer Doudna was in sixth grade, she came home one day to find that her dad had left a paperback titled The Double Helix on her bed. She put it aside, thinking it was one of those detective tales she loved. When she read it on a rainy Saturday, she discovered she was right, in a way. As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.
Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned a curiosity of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions.
The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code.
Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids?
After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020. Her story is a thrilling detective tale that involves the most profound wonders of nature, from the origins of life to the future of our species.
Informative, Entertaining, Thorougher, Balanced, and Up-to-date Some personal takeaways: 1. Scientic research, like venture investing or many other endeavors in life, rewards risk taking and audacity. You ought to aim high, pursue big dreams, and be willing...
評分这本书主要围绕Jennifer Doudna, 回顾了CRISPR和基因编辑的探讨. 写的跌宕起伏, 描述了科学研究者之间秘密竞争同时又对自然保护好奇心展开合作. 不同的研究者展示了非常不一样的个性. 后面几章讨论bioethics 和人类基因改造, 我不大喜欢. 作者自己个人想法太多,觉得有点肤浅, ...
評分 評分1、 根据我目前的认知,大部分生命活动的调控是精细而复杂的,并非敲除或改变一段序列就能产生显著效果。生命系统的复杂性也预示任意改造一段序列可能会有意外后果。此外,脱靶效应也会限制基因编辑技术的人体应用。所以,大规模的基因设计短时期内还只是个愿景,但早早开始考...
The Code Breaker 在線電子書 pdf 下載 txt下載 epub 下載 mobi 下載 2024